Phase 4 Crohn's Disease and Colitis Trial, Recruiting NCT07691138 Sponsor: University of Nottingham Condition: Crohn's Disease and Colitis
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Phase 4 Crohn's Disease and Colitis Trial, Recruiting

NCT07691138
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 16 years of age or older
  • People who have been diagnosed with Inflammatory Bowel Disease (IBD), confirmed through their primary care medical records
  • People who have been regularly taking a type of medication called a proton pump inhibitor (PPI) — a common stomach acid-reducing medicine — for more than 6 months before joining the trial
  • People who have been taking their PPI medication as prescribed, meaning they have taken more than 75% of their doses
  • People who are able to give their own full and informed consent to participate
  • People whose IBD has been stable, meaning no changes to their medication and no IBD-related surgery in the past 3 months

Who may not be able to join:

  • People who are unable to fully take part in all parts of the trial
  • People who have a condition called Barrett's oesophagus (a change in the lining of the food pipe)
  • People who had signs of peptic (stomach or digestive) disease found during a recent camera examination of their upper digestive system
  • People who have a condition called Zollinger-Ellison Syndrome, which causes excess stomach acid
  • People who have a condition called eosinophilic oesophagitis (a type of inflammation in the food pipe)
  • People who regularly use anti-inflammatory painkillers such as ibuprofen or naproxen (known as NSAIDs)
  • People who have pulmonary fibrosis (scarring of the lungs)
  • People who have declined to allow their data to be shared
  • People with a history of dementia
  • People who have a terminal illness
  • People who currently have cancer or another malignancy
  • People with an active history of mental illness
  • People who are living in a care home
  • People with alcohol misuse issues
  • People with illicit drug misuse issues

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Phone: 0115 9249924

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
University of Nottingham
Registry
ClinicalTrials.gov
Start date
1 July 2026
Est. completion
1 July 2027

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Eligibility rate; Recruitment rate; Adherence to allocated intervention; Participant retention rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov