Phase 3 Gastroparesis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have a digestive system disorder and standard treatments have not worked for you
- You have symptoms of one of the following: delayed stomach emptying (gastroparesis); heartburn or acid reflux that hasn't responded to treatment, including throat or breathing problems related to reflux; or severe indigestion
- You have had a thorough medical evaluation, including your health history and a physical exam, to rule out other causes of your symptoms
- You are willing to sign a consent form agreeing to take the study drug, domperidone
- Your white blood cell count is above a certain level (confirm with trial site)
- Your liver-related blood test results (alkaline phosphatase, ALT, AST, and bilirubin) are within acceptable ranges (confirm with trial site)
- Your kidney-related blood test results (BUN and creatinine) are within acceptable ranges (confirm with trial site)
- Your hemoglobin (a measure of healthy red blood cells) is at or above a minimum level (confirm with trial site)
- Your potassium and magnesium levels are within a specific healthy range (confirm with trial site)
Who may not be able to join:
- You have certain heart conditions, such as dangerous heart rhythm problems, a slower-than-normal heart rate, problems with your heart's electrical system, an abnormal heart rhythm reading on an ECG, significant heart valve disease, heart disease related to poor blood flow or lung problems, a weakened heart muscle, or a history of heart failure
- You are currently taking certain medications used to treat irregular heartbeats that can affect heart rhythm (such as amiodarone, quinidine, sotalol, or similar drugs)
- You are currently taking a type of antidepressant or other medication called a monoamine oxidase (MAO) inhibitor
- You have a history of liver failure or currently have liver failure
- Your sodium, potassium, or magnesium levels are outside of a safe range (confirm with trial site)
- You had bleeding in your digestive tract or a blockage in your digestive system within the past 6 weeks
- You have a type of brain tumor that causes the body to produce too much of a hormone called prolactin (called a prolactinoma)
- You are pregnant or breastfeeding; women who could become pregnant must have a negative pregnancy test before starting the study and must use effective birth control or remain abstinent during the study
- You have a known allergy to domperidone (the study drug)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Mehnaz Shafi, M.D. Anderson Cancer Center
Phone: 713-794-5073
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Attenuation of symptoms associated with disorder(s) of gastrointestinal motility, measured by change in Gastroparesis Cardinal Symptom Index (GSCI) score from baseline
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.