Phase 3 Depression and Anxiety Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People whose main drug problem is methamphetamine dependence or misuse, with methamphetamine being their primary substance of concern
• People who currently have a diagnosis of major depression (whether caused by methamphetamine use or separate from it)
• People who currently have a diagnosis of an anxiety disorder (whether caused by methamphetamine use or separate from it)
• People whose current depression rating score is 16 or higher on a standard clinical scale called the Hamilton Depression Rating Scale
• People whose current anxiety rating score is 18 or higher on a standard clinical scale called the Hamilton Anxiety Scale
• People who are taking medication for depression or anxiety, where that medication dose has remained unchanged for at least 4 weeks before the trial treatment begins

Who may not be able to join:

• People who are not able to give informed consent to participate in the trial
• People who are considered by a clinician to be at significant risk of harming themselves or others
• People whose main substance problem involves a drug other than methamphetamine
• Females who test positive for pregnancy
• People with a history of kidney disease
• People with a significant medical or neurological condition identified through their health history, a physical examination, or lab tests
• People who have previously had an allergic or hypersensitivity reaction to creatine

Important: Always verify eligibility with the trial site directly before applying.