NCT03322566

Who might be able to join this trial:

• You have been diagnosed with advanced (stage IV) non-small cell lung cancer (NSCLC) confirmed by a lab test, and your cancer does not have certain specific genetic changes (called EGFR mutations, ROS1, or ALK translocations).
• Your cancer can be measured on a scan, following specific medical guidelines (called RECIST 1.1).
• Your doctors expect you to live for at least 3 more months.
• You are generally well enough to carry out light activity and care for yourself (rated 0 or 1 on a standard health scale used in cancer trials).
• Your organs (such as liver, kidneys, and blood cells) are functioning well enough to meet the trial's requirements.
• You are able to provide a sample of your tumor tissue.

Who may not be able to join:

• You have untreated cancer that has spread to your brain or the lining around your brain or spinal cord.
• You have had lung inflammation (not caused by infection) in the past that needed steroid treatment, or you currently have lung inflammation or scarring.
• You have uncomfortable fluid build-up in your abdomen or around your lungs.
• You have had another type of cancer, unless you completed treatment at least 5 years ago with no signs of it returning.
• You have an autoimmune disease (where your immune system attacks your own body) that has needed medical treatment in the last 2 years.
• You have received an organ or tissue transplant from another person.
• You have a known history of HIV infection.
• You have active Hepatitis B or Hepatitis C (blood tests will be required to check this).
• You have an abnormal heart reading (ECG) that the trial doctor considers medically significant.
• You are currently using, or have recently used, certain medications or treatments that are not allowed by the trial rules (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.