NCT03345849

Who might be able to join this trial:

• You have been diagnosed with Crohn's disease (CD) for at least 3 months before the study starts.
• Your Crohn's disease has been confirmed as moderate to severe, based on how often you have bowel movements and your level of abdominal pain.
• A camera test (endoscopy) has shown active inflammation in your gut, confirmed by an independent reviewer.
• Previous treatments for Crohn's disease — such as steroids, immune-suppressing medicines, or biologic therapies — have not worked well enough for you, or you were unable to tolerate them.
• If you previously tried a biologic therapy but stopped it for a reason other than it not working or causing side effects (for example, insurance changes or because your disease was under control), you may still be eligible (confirm with trial site).
• If you are a woman who could become pregnant, you must be willing to follow the trial's contraception requirements.

Who may not be able to join:

• You have been diagnosed with ulcerative colitis or a form of colitis that doctors have not been able to clearly classify.
• You are not currently on a stable, consistent dose of certain Crohn's-related medicines, such as antibiotics, aminosalicylates, steroids, or methotrexate.
• You currently have serious complications from Crohn's disease, such as an abscess, a blocked bowel, severe colitis, a dangerously swollen colon, large sections of your bowel missing, or any condition that may require surgery during the study.
• You have had a stoma (ostomy bag) or a surgically created internal pouch.
• You have a condition that affects how your body absorbs medicine, such as short bowel syndrome.
• Your blood tests or other screening results come back with abnormal findings (confirm with trial site for specific details).

Important: Always verify eligibility with the trial site directly before applying.