Phase 3 Myeloma Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have a bone lesion (abnormal area) in the shaft or neck of the femur (thigh bone)
- People who are 18 years of age or older
- People who are already planned to have a preventive surgical nail inserted into one thigh bone (a procedure to strengthen the bone before it breaks)
Who may not be able to join:
- People who already have a broken bone at the site of the lesion at the time of the study
- People with a history of severely reduced kidney function (confirm with trial site)
- People with a history of peptic ulcer disease that caused bleeding or required a hospital stay
- People with a known allergy to NSAIDs (a type of pain relief medication) or aspirin
- People currently on a chemotherapy treatment plan that does not allow the use of NSAID medications
- People with a history of liver disease that prevents safe use of a medication called ketorolac (toradol)
- People with a history of heart failure or heart/blood vessel disease that prevents safe use of ketorolac (toradol)
- People who are pregnant
- People who have had a severe allergic reaction (anaphylaxis) to narcotic (opioid) medications
- People who have a blood clotting disorder, or who need to take blood thinning or anti-clotting medications during the study treatment period
- People who have had a severe allergic reaction (anaphylaxis) to acetaminophen (paracetamol)
- People currently taking a medication called probenecid
- People currently taking a medication called pentoxifylline
- People with a history of asthma triggered by aspirin
- People with a known history of opioid dependence, misuse, or addiction
- People who are planned to have the preventive surgical nail inserted into both thigh bones
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: David Greenberg, MD, St. Louis University
Phone: 314-617-3410
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Milligram Morphine Equivalent (MME) of Opioid Medications Utilized
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.