Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults between 18 and 80 years of age who have nerve pain in their back and/or lower limbs that has lasted more than 3 months after lumbar (lower back) spine surgery, confirmed by a clinical assessment and a specific pain questionnaire score
- People whose pain rates above 3 out of 10 in severity, and whose pain-related disability scores above 40 out of 100 on a standard assessment tool
- People whose pain has not been adequately controlled by standard medical treatments tried for at least 3 months
Who may not be able to join:
- People younger than 18 or aged 80 years or older
- People who have previously had a trial or permanent implant of a spinal cord stimulation (SCS) device
- People for whom the spinal cord stimulation procedure would be considered medically unsafe, such as those with extensive prior thoracolumbar spine surgery, significant narrowing of the spinal canal, blood clotting problems, or an active infection (confirm with trial site)
- People who are pregnant
- People taking high doses of opioid pain medication above a specific threshold (confirm with trial site)
- People with a psychiatric or psychological condition that is likely to affect how pain is experienced or reported
- People who would be unable to follow the study procedures or provide reliable assessments of their treatment outcomes
- People with spine instability detected on specific lumbar X-rays
- People who have an active legal or compensation claim related to their pain
- People who also have nerve or muscle conditions affecting the limbs, or nerve pain originating from the brain or spinal cord itself (such as pain following a stroke)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Anuj Bhatia, MD FRCPC, University Health Network, Toronto
Phone: (416) 603-5800
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Changes in neuronal activity with the novel PF-SCS modes as detected by fMRI and MEG; Changes in neuronal activity with the novel PF-SCS modes as detected by fMRI and MEG; To measure long-term outcomes of novel PF-SCS modes including intensity and quality of pain, physical and psychological functioning, and patients' global impression of change; Changes in sensory threshold with the novel PF-SCS modes as detected by QST
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.