Early Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting NCT04008121 Sponsor: MediBeacon Condition: Retinal Vein Occlusion and Diabetic Macular Oedema
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Early Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting

NCT04008121
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be 18 years of age or older (men and women are both welcome)
  • Women who cannot become pregnant, or women who are willing to use adequate birth control during the trial
  • Men who are willing to either avoid sexual intercourse or use adequate birth control from the day of the study dose until at least 7 days after
  • You are willing and able to follow all study requirements
  • You have read and signed a consent form agreeing to take part
  • Note: the trial aims to include at least 5 participants who currently have, or have had, a history of disease affecting the blood vessels in the back of the eye (confirm with trial site)

Who may not be able to join:

  • Women who are pregnant, breastfeeding, planning to become pregnant during the study, or unwilling to use adequate birth control
  • Anyone who has taken part in another medical research trial within the last 30 days, or is currently enrolled in another study that could affect results
  • Anyone with a history of drug or alcohol misuse within the past year
  • Anyone who has had a severe allergic reaction or life-threatening allergic response to any drug, the study drug (MB-102), fluorescein sodium, or similar products
  • Anyone with a history of seizures
  • Anyone with significant cataracts or other eye conditions that would prevent clear eye photographs from being taken
  • Staff members directly involved in running this study, or their close family members
  • Anyone who is unable to tolerate eye-imaging procedures
  • Anyone whose overall health, in the doctor's judgment, makes participation unsuitable — for example, unstable heart or other serious health conditions (confirm with trial site)
  • Anyone who has previously been enrolled and received a dose in this same study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Richard B Dorshow, PhD, MediBeacon

Phone: 314-735-0967

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
MediBeacon
Registry
ClinicalTrials.gov
Start date
6 November 2025
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Binary assessment by the Principal Investigator of the feasibility of MB-102 imaging as compared to fluorescein dye

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov