Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting NCT04187443 Sponsor: Shenzhen MingSight Relin Pharmaceuticals Co., Ltd. Condition: Retinal Vein Occlusion and Diabetic Macular Oedema
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Phase 1 Retinal Vein Occlusion and Diabetic Macular Oedema Trial, Recruiting

NCT04187443
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with type 1 or type 2 diabetes, confirmed using standard medical guidelines.
  • You are able to follow the study instructions and are expected to attend all required visits and complete all study steps.
  • You agree to use reliable birth control during the study, and if you are a woman who could become pregnant, you agree to take a pregnancy test before joining.
  • You have a specific type of eye problem related to diabetes called diabetic macular edema (swelling in the central part of the retina), confirmed by a special eye scan at your screening visit.
  • Your vision in the study eye meets a minimum level, roughly 20/200 or better, as measured by a standardized eye chart test at your screening visit.
  • Your eye doctor confirms that laser treatment or injections for your eye condition are either not needed right now or can safely be delayed for at least 3 months after your screening visit, or you have chosen not to have those treatments.
  • Your eyes can be examined clearly, meaning pupils can be dilated enough to get good quality images of the retina.

Who may not be able to join:

  • Your diabetes or blood pressure is not well controlled or is considered unstable.
  • Your body weight is either too low or too high for the study (body mass index below 18.5 or above 28 kg/m²).
  • You are currently taking, or are likely to need, certain medications known to be harmful to the eye or optic nerve, such as Deferoxamine, Chloroquine, Hydroxychloroquine, Tamoxifen, Phenothiazines, or Ethambutol.
  • You have had a heart attack, stroke, mini-stroke (TIA), heart failure treatment, or a serious heart rhythm problem requiring hospital care within the 4 months before your screening visit.
  • There is any other reason the study doctor believes it would not be safe for you to participate, that you may not be able to follow the study requirements, or that your situation could affect the study results (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Kai Zhang, MD, Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.

Phone: +8613421382136

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.
Registry
ClinicalTrials.gov
Start date
2 June 2020
Est. completion
30 October 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Treatment-emergent adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov