Gastro-oesophageal Reflux Disease Trial, Recruiting NCT04422405 Sponsor: Spital Limmattal Schlieren Condition: Gastro-oesophageal Reflux Disease
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Gastro-oesophageal Reflux Disease Trial, Recruiting

NCT04422405
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a Body Mass Index (BMI) over 35 kg/m² (a measure of body weight relative to height that indicates severe obesity)
  • People who have been following a medically supervised obesity treatment program for at least 2 years without significant weight loss
  • People who are willing to give their consent to take part in the study

Who may not be able to join:

  • People who have been in a supervised obesity treatment program for less than 2 years
  • People who have cancer
  • People who have serious liver scarring (cirrhosis) at a certain severity level known as Child-Pugh score A
  • People who have Crohn's disease (a chronic inflammatory bowel condition)
  • People who have a serious psychiatric (mental health) disorder that required a stay in a psychiatric hospital within the past two years
  • People who use illegal drugs
  • People who have shown difficulty following medical instructions or treatment plans (confirm with trial site)
  • People who have a hiatal hernia (where part of the stomach pushes up into the chest) larger than 4cm
  • People whose stomach pouch measures less than 10cm (confirm with trial site)
  • People who have Barrett's oesophagus (a condition affecting the lining of the food pipe)
  • People who have significant inflammation of the food pipe (erosive oesophagitis) at a moderate to severe level
  • People who have a narrowing of the stomach confirmed by a camera examination
  • People who have test results showing excessive acid exposure or an abnormally high number of acid reflux episodes per day
  • People whose lower food pipe muscle (lower oesophageal sphincter) shows abnormal function on specialised testing
  • People whose swallowing and reflux tests show abnormal levels of acid or non-acid reflux

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +41 44 733 21 26

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Spital Limmattal Schlieren
Registry
ClinicalTrials.gov
Start date
1 June 2020
Est. completion
28 May 2035

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Marginal ulcer rates; Marginal ulcer rates; Assessment of age as risk factor for marginal ulcer development; Assessment of age as risk factor for marginal ulcer development; Assessment of gender as risk factor for marginal ulcer development; Assessment of gender as risk factor for marginal ulcer development; Assessment of tobacco use as risk factor for marginal ulcer development; Assessment of tobacco use as risk factor for marginal ulcer development; Assessment of alcohol use as risk factor for marginal ulcer development; Assessment of alcohol use as risk factor for marginal ulcer development...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov