Gastro-oesophageal Reflux Disease
Clinical trials recruiting in Australia for Gastro-oesophageal Reflux Disease, as the public registries list them.
Also called: Gastroesophageal reflux disease; GERD; acid reflux; reflux; reflux oesophagitis
At a glance
2 trials recruiting in Australia
4 states or territories with a listed site
0 started recruiting in the last 30 days
194 trials recruiting overseas
11 October 2026 date last checked
Where the trials are
Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.
Trials for Gastro-oesophageal Reflux Disease
2 of 2 trials shown.
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Phase 2
Phase 2 study for people with Gastro-oesophageal Reflux Disease
Where- Campbelltown Private Hospital, Sydney (NSW) — Recruiting
- Mater Hospital Brisbane, Brisbane (QLD) — Recruiting
- Princess Alexandra Hospital, Brisbane (QLD) — Recruiting
- Coastal Digestive Health, Maroochydore (QLD) — Recruiting
- Royal Adelaide Hospital, Adelaide (SA) — Recruiting
- Eastern Health Box Hill, Box Hill (VIC) — Recruiting
- Northern Hospital Epping, Epping (VIC) — Recruiting
- The Alfred Hospital, Melbourne (VIC) — Recruiting
- Royal Melbourne Hospital, Parkville (VIC) — Recruiting
Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Eupraxia Pharmaceuticals Inc.TimelineStarted 31 March 2023 Today 16 October 2026 Estimated completion 1 December 2026NCT05608681 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Gastro-oesophageal Reflux Disease
Where- Melbourne Gastro Oesophageal Surgery (MGOS), Melbourne (VIC) — Recruiting
- St Vincent's Hospital Melbourne, Melbourne (VIC) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor St Vincent's Hospital MelbourneTimelineStarted 20 June 2025 Today 16 October 2026 Estimated completion 1 February 2027NCT06839248 · Checked 11 October 2026
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voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice
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Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.
Trials overseas
194 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
About Gastro-oesophageal Reflux Disease
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
What is GERD? Sometimes, after eating a large meal or lying down too soon after eating, you might feel acid coming up into your throat. This is called gastroesophageal reflux (GER). It happens when the muscle at the end of your esophagus (the tube that carries food from your mouth to your stomach) doesn't close properly. Stomach contents can then move back up and irritate the esophagus. Having reflux occasionally is common. But if you have symptoms two or more times a week or if they cause damage to the lining of your esophagus, you may have gastroesophageal reflux disease (GERD). GERD is a chronic (long-lasting) condition that can cause discomfort and, over time, lead to other health problems. Anyone can have GERD, including infants and children. What causes GERD? GERD can happen when the muscle at the bottom of your esophagus becomes weak or relaxes at the wrong time. You are more likely to have GERD if you: - Are overweight or have obesity - Are pregnant - Smoke or are around secondhand smoke - Have a hiatal hernia (when part of the stomach pushes up into the chest) Certain foods, drinks, or medicines can also make GERD worse. What are common symptoms of GERD? The most common symptom of GERD is heartburn. This is a burning feeling in your chest or throat. You can also have GERD without having heartburn. Other symptoms may include: - Tasting acid or food in the back of your mouth - A dry cough or hoarse voice - Asthma-like symptoms - Trouble swallowing Get medical help right away if you have chest pain with shortness of breath, or pain in your jaw or arm. These can be signs of a heart problem. How is GERD diagnosed? Your health care provider will ask about your symptoms and medical history. They may recommend tests such as: - Upper GI endoscopy to look at the esophagus and stomach lining with a tiny camera. - Biopsy to check a small tissue sample. - X-Ray to take pictures of the upper digestive system. - Esophageal pH test to measure how often acid backs up the esophagus and how long the acid stays there. - Esophageal manometry to check how well your esophagus moves food when you swallow. - Transnasal esophagoscopy to look for damage to the esophagus by using a small tube with a camera. How is GERD treated? Most people can manage GERD with lifestyle changes and medicine. In rare cases, surgery is needed. Lifestyle changes can include: - Eating smaller meals and avoiding lying down for at least 2-3 hours after eating - Avoiding foods that trigger symptoms, such as spicy foods, chocolate, caffeine, or fatty foods - Losing weight if needed - Raising the head of your bed - Quitting smoking Medicines can include: - Over-the-counter medicines, such as antacids - Prescription medicines If not treated, GERD can cause problems like inflammation of the esophagus, scarring, or changes in the tissue lining (Barrett's esophagus). It can also worsen asthma or cause chronic (long-term) cough or hoarseness. Can GERD be prevented? You may be able to improve symptoms of GERD by: - Avoiding alcohol and trigger foods - Eating smaller meals - Not eating close to bedtime - Wearing loose-fitting clothes - Sleeping on your left side or raising the head of your bed - Maintaining a healthy weight NIH: National Institute of Diabetes and Digestive and Kidney Diseases
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- ClinicalTrials.gov processing date: 11 May 2026.
- This page last checked by Voxsanity: 11 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
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