Phase 4 Peripheral Neuropathy Trial, Recruiting NCT04460521 Sponsor: Emily Krauss Condition: Peripheral Neuropathy
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Phase 4 Peripheral Neuropathy Trial, Recruiting

NCT04460521
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with mild to moderate carpal tunnel syndrome (CTS) in one or both wrists, confirmed by both a physical exam and a nerve conduction test (a test that measures how well electrical signals travel through the nerves), performed within the past year
  • People whose carpal tunnel syndrome symptoms have been present for at least 6 weeks
  • People who are 18 years of age or older

Who may not be able to join:

  • People who have previously had carpal tunnel release surgery on the affected wrist or hand
  • People who have received a corticosteroid (steroid) injection in the affected wrist or hand within the past 6 months
  • People whose carpal tunnel syndrome is considered severe, shown by constant pain in the wrist or hand, constant numbness or tingling in the affected area, or visible muscle wasting at the base of the thumb
  • People with a known or suspected allergy to NAC (N-acetyl cysteine, a type of supplement)
  • People currently taking certain medications that cannot be used alongside NAC, including some antibiotics or nitroglycerin (a heart medication)
  • People who are currently breastfeeding, or people who have a history of kidney stones
  • People who have a history of injury to the neck or upper part of the arm on the same side as the affected wrist
  • People whose carpal tunnel syndrome developed as a result of pregnancy
  • People who are unable to obtain a wrist splint worn at night due to financial reasons, such as lack of insurance or limited finances (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Michael Bezuhly, MD, NSHA

Phone: 902-473-7887

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Sponsor
Emily Krauss
Registry
ClinicalTrials.gov
Start date
1 April 2022
Est. completion
1 April 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Change from baseline Boston Carpal Tunnel Questionnaire (BCTQ) at 8 weeks

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov