Phase 2 Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are male or female and aged 18 or older
- People who have a diabetic foot ulcer (an open wound on the foot related to diabetes) that is not infected and does not have reduced blood flow, and that needs pressure to be taken off it to heal
- People who are able to walk around at home, with or without help from another person or a device
- People who are willing and able to sign a written consent form agreeing to take part
Who may not be able to join:
- People whose wound has been present for longer than one year
- People whose HbA1c (a measure of average blood sugar levels over time) is above 12%
- People whose blood flow to the affected leg is below a certain level, whose blood flow cannot be measured using sound wave testing, or who are being considered for a procedure to improve blood flow to that limb during the study period
- People who have an active Charcot neuropathy (a serious bone and joint condition in the foot) or a major foot shape problem that would prevent them from wearing the study's special smart boot
- People who have had an amputation above the back of the foot on the affected leg
- People who have a significant medical or mental health condition (confirm with trial site)
- People who have abnormal lab test results that could interfere with taking part in the study (confirm with trial site)
- People who are currently doing a structured exercise training program
- People who have had changes made to their mental health or sleep medications within the last six weeks
- People whose ulcer extends into the bone
- People whose foot ulcer is not caused by diabetes
- People who are unable or unwilling to attend required clinic visits or follow the study's instructions
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: David G Armstrong, DPN, MD, PhD, Professor of Surgery, Keck School of Medicine of USC
Phone: 3235162332
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Wound healing at 12 weeks or sooner; Time to wound healing
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.