Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are male or female, aged between 18 and 65 years old
- People who have normal vision and hearing, or vision and hearing that is corrected to normal (for example, with glasses or hearing aids)
- People who have been diagnosed with generalised anxiety disorder (GAD) as their main condition, at a moderate or severe level based on standard diagnostic guidelines, with a score above 17 on a specific anxiety rating scale (confirm with trial site)
- People whose anxiety disorder has been present for more than one year
- People who are considered medically stable by the study doctor
- People who have tried and not responded to at least two antidepressant medications of a specific type (SSRIs) and at least one additional treatment used alongside those medications
- People who have previously had a brain stimulation treatment called rTMS are able to join, though this is not required
Who may not be able to join:
- People whose primary anxiety diagnosis is a different anxiety disorder other than GAD (though conditions like depression alongside GAD may be permitted, as long as GAD is the main diagnosis — confirm with trial site)
- People who are currently using any mind-affecting substances or medications that have not been prescribed to them, other than medications being used to treat their GAD
- People who are unable to safely undergo an MRI scan for any reason
- People who are pregnant, may possibly be pregnant, or are planning to become pregnant in the near future
- People who would not be able to follow the treatment schedule required by the study
- People who have just started a new anxiety treatment at the time they would be assigned to a study group
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Margaret G Distler, MD,PhD, University of California, Los Angeles
Phone: (310) 794-1553
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Hamilton Anxiety Rating Scale (HAM-A)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.