Parkinson's Disease Trial, Recruiting NCT04650932 Sponsor: University of California, Davis Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT04650932
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 years or older
  • People who have been diagnosed with idiopathic Parkinson's Disease (Parkinson's with no known external cause)
  • People who have previously had a specific brand of deep brain stimulation (DBS) device implanted — the Boston Scientific Vercise™ system
  • People who have had this DBS device implanted for at least 3 months before joining the trial
  • People who have advanced Parkinson's Disease and had DBS surgery on both sides of the brain, targeting a specific brain region called the subthalamic nucleus, as part of their standard treatment for movement symptoms, with the electrode tips placed in a specific part of that region

Who may not be able to join:

  • People who are unable to give their own informed consent to take part in the trial
  • People with cognitive (thinking or memory) or physical difficulties that would prevent them from completing cognitive (thinking and memory) tests
  • People who score below 15 on a specific cognitive screening test called the Montreal Cognitive Assessment Test-Blind
  • People who score above 20 on a specific depression screening questionnaire called the Center for Epidemiologic Studies Depression Scale
  • Women who are pregnant, and people who are currently incarcerated
  • People who do not speak English, as the cognitive tasks in this trial are conducted in English only

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kiarash Shahlaie, MD, PhD, University of California, Davis

Phone: 916-703-5505

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
22 October 2022
Est. completion
30 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Mean Change from Baseline in Depression Scores on the Center for Epidemiologic Studies Depression Scale (CES-D); Mean Change from Baseline in Impulsiveness Scores on the Barratt Impulsiveness Scale (BIS-11); Mean Change from Baseline in Neuropsychiatric Inventory (NPI); Mean Change from Baseline in Movement Scores on Part III of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS); Mean Change from Baseline in Cognitive Performance Scores on the Montreal Cognitive Assessment - Blind (MoCA); Mean Change from Baseline in Depression Scores on the CES-D Short Version (CES-D-R10); Mean Change f...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov