Phase 3 Parkinson's Disease Trial, Recruiting NCT04664634 Sponsor: Northwestern University Condition: Parkinson's Disease
Back to Parkinsons Disease

Phase 3 Parkinson's Disease Trial, Recruiting

NCT04664634
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 22 years of age or older
  • People who speak English
  • People who have been diagnosed with idiopathic Parkinson's disease (Parkinson's disease with no known cause) at any stage of the disease, as confirmed by a neurologist
  • People who have mild to moderate drooling or difficulty managing saliva, based on a specific scoring tool used to measure this (confirm with trial site)
  • People whose Parkinson's medication is working at its best level during all study visits (known as the "on" phase)

Who may not be able to join:

  • People who have had a lung infection caused by inhaling saliva or food (aspiration pneumonia) in the past 12 months
  • People who cannot swallow their own saliva without using a special technique or maneuver
  • People who are currently receiving treatment for swallowing difficulties or excessive saliva
  • People who currently have problems with alcohol or drug misuse
  • People who have been diagnosed with a neurological condition other than Parkinson's disease
  • People who have advanced dementia
  • People who have a history of cancer or surgery involving the head or neck
  • People who are unable to show that they can use the study's sensor device and technology
  • People who have a known allergy to the contrast material used in a specific type of swallowing X-ray test (called MBSS)
  • People who have a known allergy to sensor adhesive (the sticky material used to attach the study sensors)
  • People who have a permanent breathing tube in their throat (tracheostomy tube)
  • People who have a feeding tube inserted through the nose (nasogastric tube)
  • People who are currently pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 251-622-7112

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
1 April 2025
Est. completion
31 May 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percent agreement with Gold Standard; Change in mean swallow frequency during haptic cueing week

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov