Phase 1 Colorectal Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 18 years of age or older, of any gender, race, or ethnic background
- People who are willing and able to sign a written consent form agreeing to take part
- People who have been diagnosed with a specific type of rectal cancer called rectal adenocarcinoma
- People whose cancer has grown into or through the rectal wall, or has spread to nearby lymph nodes, based on standard cancer staging guidelines
- People who have not yet received any treatment for their rectal cancer
- People who are reasonably active and able to care for themselves, based on a standard medical rating scale (confirm with trial site)
- People whose recent blood test results show that their blood cells, liver, and kidneys are functioning within acceptable levels (confirm with trial site)
- People who agree to use effective contraception — such as hormonal or barrier methods, or abstinence — starting from the first dose of treatment through to 90 days after the last dose. Women who become pregnant or think they might be pregnant during the trial must inform their treating doctor immediately
Who may not be able to join:
- People whose cancer has spread to distant lymph nodes (such as those in the abdomen or groin) or to other parts of the body
- People who have previously had radiation therapy to the pelvic area
- People with serious uncontrolled health conditions, such as severe heart failure, unstable chest pain, irregular heart rhythms, or mental health conditions that could make it difficult to follow the trial requirements
- People with mental health or social circumstances that would make it difficult to give informed consent or follow the trial's requirements
- People who are currently pregnant or breastfeeding, due to potential risks to the baby
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Nina Sanford, MD, UT SOUTHWESTERN medical CENTRE
Phone: 12146458525
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To determine the maximal tolerated dose (MTD) of dose-escalated hypofractionated RT.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.