Phase 2 Pancreatic Cancer Trial, Recruiting NCT04683315 Sponsor: Medical College of Wisconsin Condition: Pancreatic Cancer
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Phase 2 Pancreatic Cancer Trial, Recruiting

NCT04683315
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are suspected of having pancreatic cancer and are scheduled for a procedure (endoscopy) to take a tissue sample for diagnosis.
  • You are willing to have a tissue sample taken during an endoscopic procedure for research purposes, or you can provide a previously collected tissue sample for testing.
  • You are 18 years of age or older.
  • You are able to read and sign a consent form, or you have a legally authorized person who can do this on your behalf.
  • Your tissue sample has confirmed a specific type of pancreatic cancer called adenocarcinoma.
  • You are generally well enough to carry out daily activities with minimal limitations (confirm with trial site).
  • Your cancer has been assessed by CT or MRI scan as either removable by surgery, or borderline removable by surgery, meeting specific criteria about how much the tumor affects nearby blood vessels and other structures (confirm with trial site).
  • Your blood counts, kidney function, and liver function meet certain minimum levels as measured by blood tests (confirm with trial site).
  • If you are female, you are either past menopause, surgically unable to become pregnant, or have a negative pregnancy test and agree to use contraception before, during, and for four months after treatment.
  • If you are male, you are either surgically sterile or agree to use barrier contraception during the study and for four months after your last dose of study medication.

Who may not be able to join:

  • You have received chemotherapy or radiation therapy within the past three years.
  • You have had another type of cancer within the past three years, unless it was a fully cured skin cancer (basal or squamous cell), fully cured early-stage cervical cancer, or localized prostate cancer with normal PSA levels.
  • You have serious uncontrolled health conditions, such as an active serious infection, severe heart problems, uncontrolled irregular heartbeat, significant mental health conditions, a BMI over 55, or anything else that would make it difficult for you to follow the study requirements or give informed consent.
  • You have a known infection with HIV, hepatitis B, or hepatitis C.
  • You are currently pregnant or breastfeeding, or you are capable of becoming pregnant and are not willing to use contraception starting four weeks before treatment begins.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Kathleen K Christians, MD, Medical College of Wisconsin

Phone: 866-680-0505

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Medical College of Wisconsin
Registry
ClinicalTrials.gov
Start date
1 April 2021
Est. completion
31 December 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Subjects who receive PurIST classification-directed therapy.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov