Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older who are scheduled to have a heart rhythm procedure (called ablation — using radiofrequency, pulsed field, or cryo-balloon methods) to treat atrial fibrillation (an irregular heartbeat), in line with current medical guidelines.
- People whose atrial fibrillation causes symptoms and has either not responded to, or could not be tolerated with, certain heart rhythm medications — or who are being considered for ablation before trying those medications.
- People who are willing and able to give their agreement to take part in the trial (informed consent).
- People whose blood vessel anatomy in the chest and neck area has been assessed by a CT scan and found to be suitable for the procedure.
Who may not be able to join:
- People whose blood vessel anatomy is not suitable for the trial's special device — for example, due to poor blood flow in the right arm, or because the major blood vessels leading to the brain have significant blockages (over 70%), twisting, widening, tearing, or bulging.
- People who have had a stroke or a temporary stroke-like episode (sometimes called a "mini-stroke") within the past six months.
- People who have a carotid artery condition (in the neck) that requires treatment within the next six weeks.
- People who are unable or unwilling to give their agreement to take part.
- People who are pregnant.
- People with a known history of dementia.
- People with a known allergy or sensitivity to nickel-titanium (a metal used in some medical devices).
- People who have implanted devices in their body that are not safe for MRI scans, including certain heart devices such as pacemakers or defibrillators.
- People who have a blood clot in a specific part of the heart (the left atrium) — all patients are routinely checked for this before the procedure using ultrasound imaging.
- People whose atrial fibrillation is caused by a treatable underlying condition, such as an overactive thyroid.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Malini Madhavan, MBBS, Mayo Clinic
Phone: (507) 255-0774
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incident of overt and covert CNS injury 7 days post AF ablation; Incident of overt and covert CNS injury 90 days post AF ablation
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.