Phase 4 Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with atrial fibrillation (an irregular heartbeat condition) — whether in the past, currently, or as an ongoing condition
- People who are aged between 55 and 73 years old at the time of joining the trial
Who may not be able to join:
- People who have previously had a stroke, a mini-stroke (also called a transient ischaemic attack), or a blood clot that travelled to another part of the body
- People who have a combination of multiple known stroke risk factors — such as heart failure, high blood pressure, being aged 65 or older, diabetes, a previous heart attack, circulation problems in the legs or major blood vessels, and/or being female — where a doctor would normally start blood-thinning medication
- People who have ever had bleeding inside the brain
- People who have had a serious bleeding event requiring a hospital stay within the last 3 years
- People who have had a condition in the last 12 months that raises the risk of serious bleeding, such as stomach ulcers, certain brain or eye injuries or surgeries, abnormal blood vessels, liver disease affecting blood clotting, varicose veins in the food pipe, or certain cancers (confirm with trial site)
- People whose kidneys are not working well enough, based on a blood test result from the last 12 months
- People who have taken certain antifungal medications (ketoconazole, itraconazole, voriconazole, or posaconazole) in the last 3 months
- People who have a documented diagnosis of dementia
- People who have had an allergic reaction to or cannot tolerate blood-thinning tablets of the type known as direct oral anticoagulants
- People who are currently taking any blood-thinning medication
- People who have any medical reason that means a doctor has recommended they take blood-thinning medication
- People who are currently experiencing active, significant bleeding
- People whose life expectancy is estimated to be less than 2 years
- People who are unwilling or unable to give consent for their electronic health records to be accessed and linked for the trial
- People who are currently taking part in another clinical trial
- Women who could become pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Dipak Kotecha, University of Birmingham and University Hospitals Birmingham NHS Foundation Trust
Phone: +44 121 371 4225
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Composite primary endpoint - Time to first event
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.