Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People diagnosed with idiopathic Parkinson's disease (Parkinson's that has no known cause) who were assessed by their doctors as suitable candidates for a specific type of brain stimulation surgery called Deep Brain Stimulation (DBS) targeting an area of the brain called the subthalamic nucleus (STN).
- People who have already had both sides of the brain treated with STN DBS surgery, and who had a specific device called the Medtronic Percept PC implanted during that surgery.
- People whose medication and brain stimulation settings have been stable and well-adjusted for at least 3 months since their DBS surgery.
- People who agree to take part in the study.
- People whose brain activity showed a specific electrical signal pattern (called a beta peak) during surgery, detected at a strength of at least 0.7 µV/rtHz using specialised monitoring equipment (confirm with trial site if unsure what this means for your situation).
- People whose Parkinson's symptoms improved by at least 30% with brain stimulation, measured using a standard Parkinson's assessment scale, at least 3 months after surgery.
Who may not be able to join:
- People who do not currently have the Medtronic Percept device implanted.
- People who are not willing to take part in the study.
- People whose brain stimulation settings have been unstable and have needed frequent adjustments.
- People who have experienced significant unwanted side effects from their brain stimulation.
- People whose condition requires unusual stimulation frequencies — either very high (above 200 Hz) or very low (below 100 Hz).
- People who have an implanted heart device (such as a pacemaker).
- People whose Medtronic Percept PC device is showing a low battery warning (called "elective replacement indicated") at the time the study begins.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Aviva Abosch, MD, PhD, University of Nebraska
Phone: 402-215-3053
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety and Tolerability of novel DBS stimulation patterns.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.