Phase 2 Pancreatic Cancer Trial, Recruiting NCT04858009 Sponsor: Mayo Clinic Condition: Pancreatic Cancer
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Phase 2 Pancreatic Cancer Trial, Recruiting

NCT04858009
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 80 years old
  • People whose general health and ability to carry out daily activities meets a certain standard, as measured by a medical scoring tool called the ECOG scale (score of 2 or below, meaning the person is able to be up and about for at least half of the day)
  • People who have been confirmed through a tissue or fluid sample to have pancreatic cancer of a specific type called adenocarcinoma
  • People whose blood test results show healthy enough levels of white blood cells, infection-fighting cells (neutrophils), and platelets (cells that help blood clot)
  • People whose kidney function is within an acceptable range based on a blood test
  • People whose cancer has spread only to the lining of the abdominal cavity (the peritoneum), which may be seen on scans or confirmed through fluid samples or a surgical procedure
  • People who have already completed pre-surgery chemotherapy and whose cancer has shown a meaningful response — such as a greater than 50% drop in a tumour marker called CA 19-9, or improvement shown on scans
  • People whose spread to the abdominal lining is limited (scored 7 or below on a medical index called the PCI), and where the surgeon considers it very likely that all visible cancer can be surgically removed

Who may not be able to join:

  • People whose cancer has spread to solid organs such as the liver, lungs, or brain
  • People who have an active infection, such as pneumonia or a wound infection, that could interfere with treatment
  • Women who have a positive pregnancy test (urine or blood), or women who could become pregnant and are not willing or able to use reliable contraception and avoid breastfeeding during the study
  • People who the medical team believes would not be able to follow the study requirements or attend follow-up appointments
  • People who have previously had a serious allergic reaction to the chemotherapy used in this study — for example, a reaction that was life-threatening, required a hospital stay, or caused lasting physical harm

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Cornelius A. Thiels, DO, MBA, Mayo Clinic in Rochester

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
15 February 2024
Est. completion
1 July 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Overall survival; Progression-free survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov