Hypertension Trial, Recruiting NCT04911491 Sponsor: University of Colorado, Denver Condition: Hypertension
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Hypertension Trial, Recruiting

NCT04911491
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 50 years or older; women must be past menopause
  • People who have been diagnosed with moderate chronic kidney disease (stage 3 or 4), with kidney function that has been stable for the past 3 months
  • People who have high blood pressure that has not been fully controlled, with readings in a specific range (120–159 mmHg on the top number) taken on two separate days, and who have been on a stable blood pressure medication plan for at least 6 weeks
  • People whose weight has stayed roughly the same (within 2 kg) over the past 3 months, and who are willing to keep their weight stable during the study. People taking or planning to start a certain type of diabetes/weight medication (GLP-1 receptor agonists) would need to have had a stable weight for at least 3 months before joining
  • People who are able to give their own informed consent to take part

Who may not be able to join:

  • People whose kidney disease is advanced enough to require dialysis
  • People with serious lung conditions, such as COPD, interstitial lung disease, cystic fibrosis, or asthma that is not well controlled
  • People with a history of a collapsed lung (whether it happened on its own or from an injury that has not fully healed), or a burst eardrum that has not fully healed, or other eardrum conditions
  • People with serious health conditions where life expectancy is less than 1 year
  • People with a history of severe heart failure (where the heart is pumping at a significantly reduced level)
  • People who have been hospitalised in the past month
  • People with a high level of protein in their urine, above a specific threshold (confirm with trial site)
  • People who currently smoke
  • People who have taken immune-suppressing medications in the past 12 months (steroid use for gout may be acceptable, but steroids must not have been taken within 2 weeks of certain study tests)
  • People with a known cancer diagnosis
  • People who are unable to have an MRI scan, such as those with severe claustrophobia, certain implants or devices, or non-removable body piercings — though these individuals may still be able to participate in other parts of the study
  • People whose use of illicit drugs or alcohol, in the opinion of the research team, would make it difficult to follow the study plan

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kristen Nowak, PhD, MPH, University of Colorado, Denver

Phone: 303-724-4842

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 March 2022
Est. completion
1 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Casual Systolic Blood Pressure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov