Depression and Anxiety Trial, Recruiting (NCT04912531)

Depression and Anxiety Trial, Recruiting NCT04912531 Sponsor: Massachusetts General Hospital Condition: Depression and Anxiety

Printed from Voxsanity (voxsanity.com.au) — NCT04912531 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Depression And Anxiety

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

People who are scheduled to have one of five specific chest or heart surgeries: coronary artery bypass grafting (heart bypass surgery), aortic valve replacement, aortic valve repair, lung resection (removal of part of the lung), or esophagectomy (removal of part of the food pipe)
People who are over 18 years old
People who do not have a cognitive or psychiatric condition that would prevent them from understanding and agreeing to take part in the study

Who may not be able to join:

People whose heart is not pumping properly (cardiogenic shock) at the time of surgery
People with severe, permanent high blood pressure that cannot be treated
People who were born with a structural heart condition (congenital heart disease)
People with significant long-term kidney problems, defined by certain blood test results or those already receiving kidney replacement treatment such as dialysis
People with evidence of serious liver disease or liver failure
People who have smell-related allergies or who have lost their sense of smell

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 20 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT04912531

Sponsor: Massachusetts General Hospital

Phase: Not Applicable

Status: Recruiting

Condition: Depression and Anxiety

More information: https://clinicaltrials.gov/study/NCT04912531

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

People who are scheduled to have one of five specific chest or heart surgeries: coronary artery bypass grafting (heart bypass surgery), aortic valve replacement, aortic valve repair, lung resection (removal of part of the lung), or esophagectomy (removal of part of the food pipe)
People who are over 18 years old
People who do not have a cognitive or psychiatric condition that would prevent them from understanding and agreeing to take part in the study

Who may not be able to join:

People whose heart is not pumping properly (cardiogenic shock) at the time of surgery
People with severe, permanent high blood pressure that cannot be treated
People who were born with a structural heart condition (congenital heart disease)
People with significant long-term kidney problems, defined by certain blood test results or those already receiving kidney replacement treatment such as dialysis
People with evidence of serious liver disease or liver failure
People who have smell-related allergies or who have lost their sense of smell

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 20 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Massachusetts General Hospital

Registry

ClinicalTrials.gov

Start date

1 October 2022

Est. completion

31 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Patients who Consent to Study Participation; Number of Patients who Complete the Study; Single Ease Question (SEQ)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov