Depression and Anxiety Trial, Recruiting NCT04982757 Sponsor: Weill Medical College of Cornell University Condition: Depression and Anxiety
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Depression and Anxiety Trial, Recruiting

NCT04982757
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with major depressive disorder (depression) OR obsessive-compulsive disorder (OCD)
  • Your symptoms are rated as moderate to severe on a standard symptom checklist (confirm with trial site for exact score details)
  • You have already tried at least one standard treatment for depression or OCD (such as certain medications or a specific type of therapy) and it did not work well enough — OR you were unable to try those treatments for personal reasons, such as not tolerating the side effects or the therapy itself
  • You are either not currently taking antidepressants, OR you have been on the same stable dose of antidepressants for at least four weeks and plan to stay on that dose throughout the study
  • You are able to understand the study and give your own consent to participate

Who may not be able to join:

  • You are considered to be at immediate risk of suicide
  • You have a main psychiatric diagnosis other than depression or OCD (for example, PTSD, psychosis, or Bipolar I or II disorder) — having anxiety disorder alongside depression or OCD may still be acceptable (confirm with trial site)
  • You show signs of significant memory or thinking difficulties based on a standard cognitive test
  • You are showing signs of psychosis that would affect your ability to understand and consent to the study
  • You have had a significant problem with alcohol or drug use in the past six months
  • You recently started a new course of talk therapy within the last eight weeks before joining the study
  • You have already completed this specific accelerated TMS treatment during your current episode of depression or OCD
  • You have taken part in another clinical trial involving an experimental drug or device within the past six weeks
  • You have a significant neurological condition such as a history of moderate to severe head injury, stroke, Parkinson's disease or another movement disorder, or epilepsy
  • You have a history of seizures (other than fever-related seizures in childhood), or you take medications or have a condition that could increase the risk of seizures
  • You have metal implants or devices in your head or body that would make an MRI scan unsafe (confirm with trial site)
  • You are currently pregnant or planning to become pregnant during the study
  • Your blood tests show abnormal results for electrolytes, thyroid function, or liver function

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
7 December 2021
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percent Change in Yale-Brown Obsessive Compulsive Scale (YBOCS) scores for participants with OCD; Change in Montgomery-Asberg Depression Rating Scale (MADRS) scores for participants with treatment resistant depression

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov