Pancreatic Cancer Trial, Recruiting NCT05053555 Sponsor: M.D. Anderson Cancer Center Condition: Pancreatic Cancer
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Pancreatic Cancer Trial, Recruiting

NCT05053555
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Group A (current patients):

  • Adults aged 18 or older who have lesions (abnormal growths) in the liver
  • People with up to five liver tumors that cannot be surgically removed, where at least one of the following applies: the tumor is at least 3 cm in size; the tumor is located very close to large blood vessels; the tumor is located very close to sensitive nearby organs or structures (such as the bowel, stomach, diaphragm, or bile ducts); the tumor has a limited blood supply that makes certain standard treatments difficult to deliver; or the tumor has a large connection to blood flow leading to other vital organs

Group B (historical patients):

  • People who would have met the Group A criteria above but did not receive a specific liver treatment (called HDRBT) between 1 January 2000 and 1 January 2021

Who may not be able to join:

  • People who currently have an active infection or infectious disease
  • People with serious uncontrolled health conditions, such as an active infection, lung disease, heart failure, unstable chest pain, irregular heartbeat, or mental health or personal circumstances that would make it difficult to follow the study requirements
  • People whose cancer has spread widely throughout the body, unless the specific tumor being targeted is directly causing serious problems such as pain, blockages, or liver problems that are affecting quality of life (confirm with trial site)
  • People who are pregnant; those who are sexually active must use birth control while taking part in the study
  • People with advanced liver disease classified as Child-Pugh class C (a medical measure of liver function — confirm with trial site)
  • People whose blood bilirubin level (a marker of liver function) is above 2 mg/dl
  • People whose platelet count (cells that help blood clot) is below 50,000/ul
  • People whose blood clotting test result (called INR) is above 1.5

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Joshua Kuban, M.D. Anderson Cancer Center

Phone: 713-745-0944

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 April 2022
Est. completion
31 January 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To prospectively evaluate the clinical effectiveness of the use of high dose rate brachytherapy (HDRBT) for the treatment of both primary liver malignancies.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov