Type 1 Diabetes Trial, Recruiting NCT05054361 Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Condition: Type 1 Diabetes
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Type 1 Diabetes Trial, Recruiting

NCT05054361
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

This trial has several different groups, and the criteria differ depending on which group a person may be considered for:

Recently diagnosed group:

  • Children aged between 1 and 15 years old
  • Recently diagnosed with type 1 diabetes, based on recognised international criteria

At-risk group:

  • Children aged between 1 and 15 years old
  • Has a brother or sister with type 1 diabetes
  • Carries specific genetic markers known as HLA DR3 and DR4 (confirm with trial site)

Control group (general):

  • Children aged between 1 and 15 years old
  • Does not carry the genetic markers linked to a higher risk of type 1 diabetes
  • Does not have antibodies against pancreas-related proteins

Control group (for a stomach and intestine examination procedure):

  • Children aged between 1 and 15 years old
  • Being investigated for possible coeliac disease or stomach inflammation

Who may not be able to join:

For all groups:

  • Children who do not have health insurance coverage
  • Cases where parents or legal guardians are not able to sign the consent forms
  • Children who have a personal history of an autoimmune or inflammatory condition, other than type 1 diabetes (for the relevant groups)
  • Children who have used steroid medications (corticosteroids) in the month before joining the trial
  • Children who are pregnant
  • Children with a medical reason that would prevent the use of local anaesthetic products

For the stomach/intestine examination groups only:

  • Children under 8 years old for the recently diagnosed group requiring this procedure
  • Children under 4 years old for the control group requiring this procedure
  • Children with heart or breathing problems, irregular heart rhythm, or blood clotting conditions, or who are taking blood-thinning medications
  • Children with a known allergy to anaesthetic medications

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +33144481545

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Registry
ClinicalTrials.gov
Start date
1 January 2022
Est. completion
11 August 2026

Where this trial is recruiting

🇫🇷 France

Primary endpoints

blood MAIT cells frequency

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov