Atrial Fibrillation Trial, Recruiting NCT05116384 Sponsor: University of Rochester Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT05116384
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged over 18 years
  • People who have persistent atrial fibrillation (an irregular heart rhythm lasting more than 7 days but less than 1 year) that is causing symptoms, and whose condition meets current guidelines for a specific heart procedure called pulmonary vein isolation
  • People who have never had high blood pressure, or whose high blood pressure is well controlled on medication (with readings below specific targets)
  • People whose kidney blood vessels are suitable for the procedure, as confirmed by a special MRI scan done before the procedure
  • People who are willing to have a small heart monitor device implanted under the skin
  • People who are willing to attend all required follow-up appointments and to sign a consent form

Who may not be able to join:

  • People who are unable to safely undergo a catheter ablation procedure for atrial fibrillation — for example, those with a blood clot in the upper left chamber of the heart, or those who cannot take any blood-thinning medications
  • People who have previously had a catheter ablation procedure on the upper left chamber of the heart for any heart rhythm problem
  • People with severe heart failure (the most serious category) or with very poor heart pumping function (confirm with trial site)
  • People with a type of atrial fibrillation that comes and goes (paroxysmal), or that has lasted for more than 1 year (longstanding persistent)
  • People who have had heart bypass surgery or heart valve surgery within the past 3 months
  • People who have previously had heart valve surgery involving a mechanical replacement valve
  • People whose kidney artery anatomy makes the procedure unsuitable — including arteries that are too small or too short, arteries with significant narrowing or abnormalities, arteries that have already been treated with a balloon or stent procedure, or people with multiple main arteries supplying either kidney
  • People with significantly reduced kidney function, as measured by a standard blood test (confirm specific threshold with trial site)
  • People with any medical condition where life expectancy is less than 1 year

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 9734364155

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
30 July 2023
Est. completion
30 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

AF burden

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov