Phase 1 Pancreatic Cancer Trial, Recruiting NCT05141513 Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Condition: Pancreatic Cancer
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Phase 1 Pancreatic Cancer Trial, Recruiting

NCT05141513
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are over 18 years old
  • People who have pancreatic cancer that has been classified as resectable, borderline resectable, or locally advanced, confirmed through CT scan, ultrasound, or other imaging
  • People who are in reasonably good general health, as measured by a standard medical scoring system (ECOG score of 0–2) (confirm with trial site)
  • People who have been fully informed about the study and have signed a written consent form approved by the relevant review board
  • People whose cancer is suitable for a specialised type of radiation treatment (SBRT) at Johns Hopkins University
  • People who are receiving initial treatment with a combination chemotherapy regimen
  • People whose case is suitable for surgical exploration at Johns Hopkins University

Who may not be able to join:

  • People who have previously had radiation therapy to the chest or abdomen
  • People who are not able to receive SBRT treatment at Johns Hopkins University
  • People whose cancer appears to have grown into the duodenum (part of the small intestine), as seen on imaging
  • People whose tumour is located in the body or tail of the pancreas (rather than the head)
  • People who are not able to undergo a Whipple procedure (a specific type of pancreatic surgery)
  • People whose cancer appears to have spread beyond the pancreas
  • People whose surgery would require reconstruction of any arteries
  • People who are currently taking part in another clinical trial involving an experimental drug or device that would interfere with this study
  • People who are unable to follow the study requirements or attend follow-up appointments
  • Women who could become pregnant, or men with female partners who could become pregnant, who are unwilling or unable to use an accepted method of contraception for the full duration of the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Amol Narang, MD, JHU, School of Medicine, SKCCC

Phone: 410-502-3828

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
6 May 2022
Est. completion
1 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Acute post-operative toxicity of targeted IORT

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov