Myeloma Trial, Recruiting NCT05160584 Sponsor: Janssen Pharmaceutica N.V., Belgium Condition: Myeloma
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Myeloma Trial, Recruiting

NCT05160584
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been officially diagnosed with multiple myeloma (a type of blood cancer) according to recognised international standards.
  • You are generally able to carry out daily activities with little to no limitation (your doctor rates your physical ability as 0, 1, or in some parts of the study, 2 on a standard scale).
  • You are not currently pregnant and do not plan to become pregnant during the study.
  • You are willing to sign a consent form showing you understand the study and agree to take part, before any study-related information is collected.
  • For some parts of the study: You have already received at least 3 previous rounds of treatment for your myeloma, and completed at least one full cycle of each, unless your cancer got worse during that treatment.
  • For some parts of the study: Your myeloma has been confirmed to be getting worse based on your doctor's assessment using recognised guidelines.
  • For some parts of the study: Your myeloma can be measured through blood or urine tests showing certain abnormal protein levels, at the time of screening.
  • For some parts of the study: Your previous treatments included three specific types of therapy — a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody (confirm with trial site if unsure which medicines these refer to).
  • For other parts of the study: Your previous treatments also included a therapy targeting a protein called BCMA, in addition to the three types listed above (confirm with trial site).
  • For another part of the study: You are starting a treatment called talquetamab for multiple myeloma that has come back or stopped responding to treatment, and this decision was made separately from the decision to join the study.

Who may not be able to join:

  • You are currently pregnant or plan to become pregnant during the study period.
  • You have not signed the required consent form before study data collection begins.
  • For some parts of the study: You have not had at least 3 previous lines of myeloma treatment (confirm with trial site for exact requirements).
  • For some parts of the study: Your myeloma cannot be measured through standard blood, urine, or imaging tests at the time of screening (confirm with trial site).
  • For the talquetamab part of the study: Your talquetamab treatment started more than 21 days before you signed the consent form, or is planned to start more than 28 days after screening begins (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Janssen Pharmaceutica N.V., Belgium Clinical Trial, Janssen Pharmaceutica N.V., Belgium

Phone: 844-434-4210

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Janssen Pharmaceutica N.V., Belgium
Registry
ClinicalTrials.gov
Start date
18 November 2021
Est. completion
30 April 2028

Where this trial is recruiting

🇦🇹 Austria 🇧🇪 Belgium 🇫🇷 France 🇩🇪 Germany 🇬🇷 Greece 🇮🇹 Italy 🇳🇱 Netherlands 🇵🇹 Portugal 🇷🇴 Romania 🇪🇸 Spain 🇨🇭 Switzerland 🇬🇧 United Kingdom

Primary endpoints

Overall Response Rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov