Atrial Fibrillation Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are scheduled to have a catheter ablation procedure for atrial fibrillation (AF), with a confirmed AF diagnosis within the past 12 months before enrolling.
• People who have had one previous ablation procedure to isolate the pulmonary veins (using cryo, radiofrequency, or pulsed field techniques) may also be considered for this trial.
• People who are between 18 and 75 years of age (inclusive).

Who may not be able to join:

• People who have medical reasons that would prevent them from safely undergoing open heart surgery if needed.
• People who are currently a patient in an Intensive Care Unit.
• People who have an active widespread infection in the body (sepsis).
• People who have had any previous ablation procedure in either the left or right chamber of the heart (confirm with trial site, as this interacts with the repeat ablation inclusion criterion above).
• People who have received a heart transplant, or who are waiting for a heart transplant or other heart surgery.
• People who have certain implanted cardiac devices that could interfere with the trial equipment, such as a device used to close a hole between the upper heart chambers, or a device that blocks the left atrial appendage.
• People who have mitral valve prolapse or other significant heart valve problems, except for mild to moderate mitral valve leakage.
• People with moderate to severe heart failure (classified as New York Heart Association Class III or IV).
• People with a history of a blood clot-related event, including stroke or a mini-stroke (TIA).
• People with a history of a bleeding disorder.
• People with a known sensitivity or allergic reaction to anesthesia or muscle-relaxing medications used during procedures.
• People who are currently on long-term steroid treatment (not including occasional use of inhaled steroids for breathing conditions).
• People who have had a heart attack within the past three months.
• People who have a significant blockage in the heart's electrical conduction system (second or third degree AV block).
• People whose heart's pumping function is significantly reduced (left ventricular ejection fraction below 35%).
• People who have unstable chest pain (unstable angina).

Important: Always verify eligibility with the trial site directly before applying.