Gastro-oesophageal Reflux Disease Trial, Recruiting NCT05180253 Sponsor: University of Louisville Condition: Gastro-oesophageal Reflux Disease
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Gastro-oesophageal Reflux Disease Trial, Recruiting

NCT05180253
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 85 years old
  • People who have never had surgery before
  • People who have no symptoms related to the stomach or food pipe (esophagus), based on standard questionnaires
  • People who are not currently taking any medications that affect stomach acid or the movement of food through the digestive system
  • People with no history of cancer
  • People who are able to understand and agree to the study terms without mental health conditions getting in the way
  • People who have never smoked
  • People who do not drink alcohol excessively or daily
  • People with a Body Mass Index (BMI) below 30
  • People with no known hiatus hernia (a condition where part of the stomach pushes up into the chest)
  • People with no known medical conditions, such as autoimmune or neurological diseases, that could affect how the food pipe or stomach works
  • People who are not allergic to fentanyl or midazolam (sometimes called Versed), which are medications used during certain procedures
  • People with no history of an eating disorder
  • People with no history of autoimmune disorders

Who may not be able to join:

  • People under 18 years of age
  • People who have had surgery involving the digestive tract
  • People currently taking medications that affect stomach acid or digestive movement
  • People with a personal history of cancer
  • People whose mental health conditions may prevent them from giving informed consent
  • People who report symptoms on standard clinical questionnaires related to the stomach or food pipe
  • People who are currently pregnant, as pregnancy can affect how the stomach and food pipe function, which could interfere with study results
  • Women who are currently breastfeeding, as the study procedures are time-consuming and involve medications that may affect the ability to nurse

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Louisville
Registry
ClinicalTrials.gov
Start date
9 January 2023
Est. completion
1 June 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Normative mucosal integrity values; Normative pyloric FLIP values

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov