Peripheral Neuropathy Trial, Recruiting NCT05204472 Sponsor: Insel Gruppe AG, University Hospital Bern Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT05204472
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 75 years
  • People who have given their signed agreement to take part
  • People living with long-term (more than 12 months) neuropathic pain on one side of the body caused by a stroke (either a blocked or bleeding blood vessel in the brain)
  • People living with long-term (more than 12 months) neuropathic facial pain on one side of the face caused by one of the following: shingles (post-herpetic neuralgia), a physical injury to a nerve in the face, or atypical trigeminal neuralgia that developed after a surgical procedure
  • People whose pain is severe (rated above 6 out of 10) and has not responded adequately to medication for nerve pain, including at least anti-seizure medications and antidepressants, tried at appropriate doses and for sufficient periods of time

Who may not be able to join:

  • People with significant problems with memory or thinking (as measured by a standard cognitive test)
  • People with a diagnosed psychiatric condition (as defined by the DSM-IV diagnostic system, covering a range of mental health disorders) (confirm with trial site)
  • People with certain psychosocial risk factors, including a history of other long-term pain conditions, a pattern of catastrophic thinking about pain, substance misuse, or situations where there may be personal benefit from remaining in pain
  • People for whom surgery, anaesthesia, or MRI scanning would not be medically safe
  • People who are unlikely or unable to properly operate the deep brain stimulation (DBS) device used in this trial
  • Women who are able to become pregnant
  • People who are unable to follow the study procedures due to language barriers, psychological difficulties, dementia, or similar reasons
  • People who have taken part in another interventional clinical trial in the 30 days before this trial, or who are currently in another such trial
  • People who have previously been enrolled in this same trial
  • Family members, employees, or other dependants of the researchers running the trial
  • People who are expected to need diathermy (a heat-based medical treatment), electroshock therapy, or transcranial magnetic stimulation (TMS)
  • People who already have an electrical device implanted in their body, such as a cardiac defibrillator or pacemaker
  • People considered to be at high risk from surgery, for example due to multiple serious illnesses or an active widespread infection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Andreas Nowacki, MD, Insel Gruppe AG, University Hospital Bern

Phone: +41 31 6320014

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Insel Gruppe AG, University Hospital Bern
Registry
ClinicalTrials.gov
Start date
1 September 2022
Est. completion
1 August 2026

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

Percentage reduction of pain intensity; Percentage reduction of pain intensity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov