Atrial Fibrillation Trial, Recruiting NCT05227053 Sponsor: Medtronic Cardiac Ablation Solutions Condition: Atrial Fibrillation
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Atrial Fibrillation Trial, Recruiting

NCT05227053
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) that is causing symptoms
  • You are 18 years of age or older (or meet the minimum age required in your country)
  • Your doctor is planning to treat your condition using a specific approved freezing procedure on the veins connected to your heart (called pulmonary vein isolation using the Arctic Front cryoablation system)
  • You are willing to follow the study requirements and sign a consent form agreeing to take part voluntarily

Who may not be able to join:

  • You have previously taken certain heart rhythm medications (called class I or III antiarrhythmic drugs, including sotalol) specifically to prevent your irregular heartbeat from coming back — though there are some exceptions to this, such as if you took the medication for less than 4 weeks before your procedure, or took a lower-than-standard dose within the last 6 months (confirm with trial site)
  • You have previously had a heart ablation procedure, unless it was a specific type done for a different heart rhythm problem called atrial flutter (CTI ablation) — that type is allowed
  • You are already taking part in another clinical study that has not been given special permission to run alongside this one
  • You meet any additional exclusion requirements set by the laws or regulations in your country (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Khaldoun Tarakji, MD, Medtronic CAS Chief Medical Officer

Phone: 800-633-8766

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Medtronic Cardiac Ablation Solutions
Registry
ClinicalTrials.gov
Start date
28 April 2022
Est. completion
1 April 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Freedom from Atrial Fibrillation (AF) /Atrial Flutter (AFL) /Atrial Tachycardia (AT); Freedom from Primary Safety Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov