Parkinson's Disease Trial, Recruiting NCT05268887 Sponsor: Massachusetts Institute of Technology Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT05268887
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Parkinson's disease (the standard kind, with no other known cause) by a specialist, with slowness of movement plus at least one of: tremor at rest or muscle stiffness.
  • Your Parkinson's symptoms are at a moderate level — not very mild and not very severe (stage 2 to 3 on a standard scale).
  • You scored 26 or higher on a standard memory and thinking test called the MoCA.
  • You are between 46 and 89 years old.
  • You can speak, read, and understand English.
  • You are able to give written consent to take part.
  • You have been on a steady, unchanged dose of your Parkinson's medications for at least one month before the study starts, and are willing to keep that dose the same throughout the study.
  • You have already had a brain CT or MRI scan to rule out other causes of your symptoms.

Who may not be able to join:

  • Your Parkinson's-like symptoms are caused by something else, such as medications, another brain disease, a stroke-related condition, or conditions like Progressive Supranuclear Palsy, Multiple System Atrophy, or Lewy Body dementia.
  • You have a history of a psychiatric illness that could create a safety concern.
  • You have been diagnosed with dementia or another neurological condition.
  • You are currently taking sedative (calming/sleep) medications that would be unsafe in this context.
  • Your medications have changed in the last month.
  • You have had recent issues with drug or alcohol misuse.
  • Your lab test results show something that could be a safety risk (confirm with trial site).
  • You are currently in, or have taken part in, another clinical trial within the last 3 months.
  • You are pregnant.
  • You do not have health insurance or healthcare coverage.
  • You have had epilepsy, a stroke, or a seizure in the past 24 months.
  • You have a diagnosis of migraines.
  • You have certain implanted medical devices in your body (confirm with trial site).
  • You have any reason you cannot safely have an MRI scan.
  • Your life expectancy is less than 2 years.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Li-Huei Tsai, PhD, Massachusetts Institute of Technology

Phone: 617-258-7723

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Massachusetts Institute of Technology
Registry
ClinicalTrials.gov
Start date
9 February 2022
Est. completion
1 November 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Feasibility of gamma frequency stimulation; Incidence of Stimulation-Related Adverse Events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov