Parkinson's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have a brain stimulation device (deep brain stimulator) already implanted, specifically a Boston Scientific Gevia™ or Genus™ R16 model, that has been approved by the FDA for use with your other device components.
• You are currently being treated with carbidopa/levodopa and/or a dopamine-boosting medication, at the best doses as recommended by a movement disorders specialist.
• Your brain stimulation device has already been shown to improve your movement and motor symptoms.

Who may not be able to join:

• You are unable or unwilling to understand what the study involves, or you are unwilling to sign a consent form agreeing to take part.
• You are unable or unwilling to attend scheduled visits and follow study procedures.
• Your medications have changed or been adjusted within the last 28 days before starting the study.
• Your brain stimulator settings have been changed within the last 28 days before starting the study.
• You are younger than 21 or older than 80 years of age.
• You are a woman who is breastfeeding, pregnant, or of childbearing age and not using adequate birth control (as decided by the study doctor).
• You have a serious illness where you are not expected to live beyond one year.
• You have a history of seizures that happened more than once or without a clear cause.
• You currently have a diagnosis of drug or alcohol addiction or misuse.
• Your Parkinson's disease is in a very advanced stage — meaning you are unable to walk on your own, or you need a walking aid to complete a specific walking test used in the study.
• You have a condition that makes walking difficult or could affect the study results, such as joint problems, nerve damage in your limbs, hip or knee replacements, or any vision or physical issue affecting how you walk.
• You have severe, disabling involuntary movements (uncontrolled movements caused by your Parkinson's medication).
• You have previously attempted suicide, or you are currently having thoughts of suicide (as measured by a standard assessment tool used in the study).
• At the time of joining, you do not pass a specific test that checks whether your brain stimulator is working correctly in both sides of your brain (confirm with trial site).
• Your walking pattern during a specific movement test does not show enough irregularity in a way required for the study to measure changes (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.