Parkinson's Disease Trial, Recruiting NCT05347407 Sponsor: Weill Medical College of Cornell University Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT05347407
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 45 and 75 years old
  • People who have been diagnosed with Parkinson's Disease, or who are considered at risk of developing it (such as those with a sleep condition called REM sleep behavior disorder, or those who have a parent, sibling, or child with Parkinson's or a related condition)
  • People diagnosed with conditions related to Parkinson's disease, including Lewy Body Dementia or Multiple System Atrophy (both caused by a similar process in the brain)
  • People whose Parkinson's disease falls within a certain range of severity, based on a standard medical scale called Hoehn & Yahr, stages 1 to 4 (confirm with trial site)
  • People who are medically able to have a colonoscopy (a camera examination of the large bowel)
  • People who are able to understand and agree to take part in the study

Who may not be able to join:

  • People whose symptoms suggest a brain or nerve condition other than the group of conditions mentioned above
  • People diagnosed with certain other brain or nerve conditions, such as Alzheimer's disease, epilepsy, stroke, multiple sclerosis, Progressive Supranuclear Palsy, Corticobasal syndrome, or a primary mitochondrial disorder
  • People with a serious ongoing illness that is expected to shorten life expectancy to less than 24 months, or a serious medical condition that is not well managed
  • People with signs of active cancer or other significant abnormalities found on a chest X-ray
  • People with active or untreated conditions affecting the stomach or bowel
  • People who cannot safely stop taking blood-thinning or anti-clotting medications, even temporarily
  • People with a history of alcohol or drug misuse (including barbiturates, cannabis, or amphetamines) within the last 5 years
  • People for whom a colonoscopy or the associated anaesthetic is not medically safe
  • People who are pregnant
  • People whom the trial doctor considers unsuitable for the study for any other reason

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jacqueline Burre, PhD, Weill Medical College of Cornell University

Phone: 929-989-7898

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
30 December 2020
Est. completion
30 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Biochemical changes in enteric nervous system

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov