Parkinson's Disease Trial, Recruiting NCT05400174 Sponsor: University of California, San Diego Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT05400174
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with idiopathic Parkinson's disease (Parkinson's that does not have a known cause) using a specific set of diagnostic guidelines called the MDS Clinical Diagnostic Criteria
  • People who are at least 50 years old
  • People who are in the early to moderate stages of Parkinson's disease (stages I–III on the Hoehn & Yahr scale), meaning they are able to walk without assistance
  • People who speak English at a native speaker level

Who may not be able to join:

  • People who have involuntary movements (such as tremor or abnormal, uncontrolled movements called dyskinesia) that are larger than 3 cm in range and are not controlled by medication, as this can interfere with the blood pressure monitoring equipment used in the study
  • People who have dementia, including dementia related to Parkinson's disease
  • People who have previously had deep brain stimulation (DBS) surgery, which is a procedure where a device is implanted in the brain to help control movement symptoms
  • People who currently have an unstable or active serious medical condition, such as severe heart failure, liver failure, or pneumonia
  • People who have moderate or severe narrowing of the carotid arteries (the main blood vessels in the neck that supply blood to the brain), as determined by a specific medical standard (confirm with trial site)
  • People who have a history of stroke, whether caused by a blocked blood vessel or bleeding in the brain
  • People who have uncontrolled diabetes or any other ongoing illness that affects the body's automatic nervous system (the system that controls things like heart rate and blood pressure without conscious effort)
  • People who have fainted within the past week
  • People who are unable to read
  • People who are currently taking medications to lower blood pressure (such as clonidine, hydralazine, verapamil, diltiazem, or medications whose names end in "-olol", "-artan", or "-pril"), water pills (diuretics such as furosemide, hydrochlorothiazide, or spironolactone), or medications for an enlarged prostate (such as prazosin, terazosin, doxazosin, alfuzosin, or tamsulosin) — note: people taking these medications are encouraged to speak with their prescribing doctor about whether it may be safe to stop taking them for 48 hours before the study visit, as this may affect eligibility
  • People who have hearing or vision problems that cannot be corrected with hearing aids or glasses
  • People who are currently pregnant (women who could potentially be pregnant will be asked to take a urine pregnancy test to confirm)
  • People who, in the opinion of the trial investigators, have any other condition that could put them at increased risk by participating

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 8588225751

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
14 December 2021
Est. completion
15 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Delis-Kaplan Executive Function System Verbal Fluency Test score (number of words per minute). Minimum: 0; Maximum: N/A; higher is better; Oxygenated and deoxygenated hemoglobin change from baseline

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov