Phase 4 Gastro-oesophageal Reflux Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People between 5 and 21 years of age
• People who receive more than 90% of their calories through a feeding tube and do not eat or drink by mouth
• People who have been identified as being at high risk of aspiration pneumonia (where food or liquid enters the airway), based on a specific swallowing test using video imaging that showed problems protecting the airway
• People who have a stable, non-worsening neurological condition (such as cerebral palsy) that causes physical or intellectual impairment and is not expected to get worse for at least one year
• People who have ongoing breathing-related symptoms — such as coughing, choking, or needing suctioning to clear the airway — at least three times per week over the past four weeks

Who may not be able to join:

• People whose neurological condition is progressive (meaning it is expected to worsen over time)
• People who have previously had a specific stomach surgery called a Nissen fundoplication that remains intact
• People who are currently taking any antibiotics, whether by mouth or inhaled, including those taken regularly to prevent infection
• People who are currently taking, or have taken in the last four weeks, medications that reduce stomach acid (such as H2 blockers or proton pump inhibitors)
• People who are fed through a tube that goes past the stomach into the small intestine (gastrojejunostomy), rather than through a standard stomach feeding tube (gastrostomy)

Important: Always verify eligibility with the trial site directly before applying.