Pancreatic Cancer Trial, Recruiting NCT05463796 Sponsor: Dana-Farber Cancer Institute Condition: Pancreatic Cancer
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Pancreatic Cancer Trial, Recruiting

NCT05463796
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who carry known gene changes (mutations) that raise their risk of developing cancer
  • People with a personal or family history that suggests a higher-than-average cancer risk, even if genetic testing came back negative or has not been done
  • People who have been clinically diagnosed with a condition that increases cancer risk, such as neurofibromatosis, Fanconi Anemia, or Ataxia-Telangiectasia
  • People identified by a cancer risk prediction tool as being at elevated risk
  • People at higher cancer risk due to factors such as past exposures, obesity, gender, race, ethnicity, or HPV exposure
  • Childhood or adult cancer survivors whose treatments may have increased their future cancer risk
  • People with documented high-level exposure to substances officially classified as cancer-causing (Group 1 carcinogens)
  • People at risk for lung cancer, for example those over age 50 with a significant smoking history or a close family member with lung cancer or COPD
  • People with certain liver conditions, such as alcoholic liver disease, fatty liver disease, or cirrhosis
  • People with certain pre-cancerous breast changes, such as ductal or lobular carcinoma in situ or atypical cell growth
  • People with certain pre-cancerous digestive conditions, such as Barrett's esophagus, pancreatic precursor lesions, or colon polyps/dysplasia
  • People with certain pre-cancerous conditions of the urinary or reproductive system (confirm with trial site)
  • People with certain pre-cancerous lung findings, such as abnormal cell growth or lung nodules found on a screening scan that need further monitoring
  • People with pre-cancerous conditions of the mouth, head, or neck area
  • People with certain pre-cancerous skin conditions, such as specific melanocytic lesions or squamous dysplasia
  • People with certain early blood or bone marrow conditions that may develop into blood cancers, such as CHIP (clonal hematopoiesis of indeterminate potential), MGUS (abnormal proteins in the blood), smoldering myeloma, or low-grade lymphomas
  • People with certain pre-cancerous gynecological conditions, such as early changes in the fallopian tubes, uterus, cervix, or vulva
  • Children with certain tissue findings sometimes linked to future cancer risk, such as kidney rests, certain bone lesions, or Spitz nevus
  • Family members of people at cancer risk, or healthy individuals

Who may not be able to join:

  • There are currently no exclusion criteria for this study — the trial states that almost anyone may be eligible to participate
  • People with a previous cancer diagnosis are still allowed to join
  • People with a history of non-spreading (non-metastatic) localized cancers, such as skin cancer or localized prostate cancer, are still allowed to join
  • People already enrolled in other clinical trials or receiving treatment for a pre-cancerous condition are still allowed to join

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Sapna Syngal, MD, Dana-Farber Cancer Institute

Phone: 857-215-1892

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
25 April 2023
Est. completion
25 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Identify exposures as well as clinical, molecular, and pathological changes that can be used to predict early development of cancer, malignant transformation, and risks of progression to symptomatic cancer that can ultimately be fatal.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov