Peripheral Neuropathy Trial, Recruiting NCT05492188 Sponsor: Medical University of South Carolina Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT05492188
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have had a spinal cord injury for more than one year and whose condition is neurologically stable.
  • People who have received medical clearance from a doctor to participate in the trial.
  • People who are able to stand, with or without a walking aid or support device, for at least 3 minutes at a time.
  • People whose current medications are expected to remain unchanged for at least 3 months (stable use of anti-spasticity medication is acceptable).
  • For people with nerve pain, the area of nerve pain must include the lower leg.

Who may not be able to join:

  • People who have an injury affecting the motor neurons (the nerve cells that directly control muscle movement).
  • People with a known heart condition.
  • People with a medically unstable condition, including those who are pregnant.
  • People with cognitive impairment (difficulties with thinking, memory, or understanding).
  • People with peripheral neuropathy (nerve damage in the limbs) that is not well controlled.
  • People who frequently use electrical spinal stimulation — either through the skin or surgically implanted — for pain management.
  • People who use electrical stimulation to the leg on a daily basis.
  • People who have a complete absence of skin sensation around the foot.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Aiko Thompson, PhD, Medical University of South Carolina

Phone: 843-792-6313

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
27 March 2023
Est. completion
1 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in minimum stimulation intensity required to barely detect the sensation (perceived threshold, perT); Change in minimum intensity at which the sensation covers the maximum area of skin (radiating threshold, RT); Change in minimum intensity at which the stimulus become painful (pain threshold, PainT); Change in pain as measured by the McGill Pain Questionnaire (MPQ); Change in neuropathic pain as measured by the Neuropathic Pain Symptom Inventory (NPSI)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov