Gastro-oesophageal Reflux Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have a moderate-to-severe or severe leaky mitral heart valve (called mitral regurgitation) that is causing symptoms, OR you have a moderately leaky mitral valve combined with a narrowed mitral valve, along with calcium buildup around the valve
- A specialist heart team at the trial site has reviewed your case and agreed that standard surgery or approved catheter-based repair treatments are not suitable for you
- You are willing and able to return for all required follow-up appointments after the procedure
- You meet the minimum legal age required to give consent in your country
- The shape and structure of your heart is suitable for the specific device being tested in this trial (the Medtronic Intrepid™ system)
Who may not be able to join:
- Your life expectancy is estimated to be less than 24 months
- You already have a surgically implanted artificial mitral valve
- You have previously had a catheter-based mitral valve procedure and that device is still in place
- Your heart anatomy is not compatible with the procedure (confirm with trial site)
- You have severe calcium buildup around the mitral valve that makes the procedure impossible
- You have aortic valve disease that needs treatment, or you had aortic valve treatment within the last 90 days
- Your heart pumping strength (ejection fraction) is below 25%; if it is between 25–30%, a review committee will assess whether you can still participate
- The lower left chamber of your heart is enlarged beyond a certain size
- You need emergency or urgent heart surgery
- Your heart is not pumping well enough to keep your body stable (confirm with trial site)
- You have a history of serious bleeding problems or a condition where your blood does not clot properly
- You have advanced kidney disease requiring dialysis or similar treatment
- You have liver failure
- You have been assessed as significantly frail
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Thomas Modine, Prof., University Hospital, Bordeaux
Phone: +31 (0)43 356 6566
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety: all-cause mortality at 1-year post-procedure.; Efficacy: Percentage of subjects with none/trace or mild mitral regurgitation at 30 days post-procedure.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.