Phase 2 Lung Cancer Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who have chosen to take part voluntarily and have signed a consent form agreeing to join the study.
- People aged 18 to 75 years old, of any gender.
- People who have been diagnosed with advanced non-small cell lung cancer (a type of lung cancer), confirmed through a tissue or cell sample, or whose lung cancer has come back after previous treatments such as surgery, radiation, or a combination of chemotherapy and radiation.
- People who have at least one tumour that can be measured using standard imaging guidelines (confirm with trial site).
- People who have a good general level of physical functioning, rated 0 or 1 on a standard scale used by doctors to assess daily activity ability (confirm with trial site).
- People who are expected to live for at least 3 more months.
- Women who are able to become pregnant must have a negative blood pregnancy test within 3 days before the first treatment dose, and must not be breastfeeding at the time of joining.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have brain tumours that have not been treated and are causing symptoms, or who have cancer that has spread to the lining of the brain, spinal cord, or similar areas.
- People who have uncontrolled build-up of fluid around the lungs, heart, or abdomen that is causing symptoms.
- People who have had another type of cancer in the past 3 years, or who currently have another cancer at the same time.
- People who have any active or known condition where the immune system attacks the body (autoimmune disease).
- People who have taken steroid medicines (such as prednisone at more than 10 mg per day, or an equivalent dose of another steroid) or other medicines that suppress the immune system within the 2 weeks before starting the trial.
- People who have severe or uncontrolled eye conditions that, in the opinion of the trial doctor, may put them at increased risk.
- People who have heart conditions or heart-related symptoms that are not well managed or controlled.
- People who have high blood pressure that is not well controlled despite taking blood pressure medication.
- People who have experienced a significant bleeding event (grade 2 or higher) or coughed up blood (2 ml or more in a single episode) within the 2 weeks before starting the trial, or who have noticeable bleeding symptoms or a known tendency to bleed.
- People who have had a serious infection within 1 month before starting the trial — including infections that required a hospital stay, bacteria in the bloodstream, or severe pneumonia — or who have taken antibiotics within 1 week before starting, or who currently have an active infection requiring intravenous (drip) treatment, or who have an unexplained fever above 38.5°C before starting.
- People who currently have, or have previously had, inflammatory lung disease (such as interstitial lung disease or radiation-related lung inflammation) that required steroid treatment, or who currently have active pneumonia (a lung infection).
- People who currently have active tuberculosis (TB) of the lungs.
- People who are known to be HIV-positive or have AIDS, or who have active hepatitis B or hepatitis C.
- People who have received radiation therapy to the lungs within 6 months before starting the trial; or who have had major surgery (not including surgery done only to diagnose a condition), chemotherapy, immunotherapy, or another experimental treatment within 4 weeks before starting; or who have received palliative (symptom-relief) radiation within 2 weeks before starting; or who stopped taking targeted therapy medicines less than 5 half-lives ago (confirm with trial site); or who have not yet recovered from side effects or complications of previous treatments to an acceptable level (confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying."
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Phone: 0518-82342973
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Primary endpoints
Dose limiting toxicity （Phase Ib）; The incidence and severity of ≥ grade 3 treatment-related adverse events (TRAE) and serious adverse events (TRSAE) in the combination of two drugs （Phase Ib）; PFS rate at 12 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 24 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.