Phase 2 Pancreatic Cancer Trial, Recruiting NCT05518903 Sponsor: Mayo Clinic Condition: Pancreatic Cancer
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Phase 2 Pancreatic Cancer Trial, Recruiting

NCT05518903
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults over 18 years old who have been diagnosed with pancreatic ductal adenocarcinoma (a type of pancreatic cancer), either confirmed by a tissue sample (biopsy) or by imaging scans such as CT, MRI, or PET, and have not yet received any treatment for it
  • People whose cancer is located in one area and who are expected to have surgery to remove it after first receiving pre-surgery treatment
  • People who are reasonably healthy and able to carry out daily activities, ranging from fully active to capable of self-care but unable to work (confirm with trial site)
  • People who are able to understand and sign a consent form agreeing to take part

Who may not be able to join:

  • People who have a known allergy or sensitivity to any of the ingredients in the imaging agent used in this trial (called 68Ga-FAPI-46)
  • People who need emergency surgery
  • People whose biopsy shows a different type of cancer, not pancreatic ductal adenocarcinoma
  • People whose pancreatic ductal adenocarcinoma has been confirmed by tissue testing to have spread to other parts of the body
  • Women who are pregnant or currently breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
15 November 2022
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Diagnostic performance of fibroblast-activation-protein-inhibitors (FAPI) positron emission tomography (PET) for detection and quantification of cancer-associated fibroblasts (CAFs) in pancreatic ductal adenocarcinoma (PDA); Relationship between 68Ga-FAPI-46 PET metrics in PDA; Relationship between 68Ga-FAPI-46 PET metrics and cancer antigen 19-9 (CA19-9) biomarkers in PDA; Relationship between 68Ga-FAPI-46 PET metrics and Kirsten rat sarcoma (KRAS), circulating tumor deoxyribonucleic acid (ctDNA) biomarkers in PDA; Relationship between 68Ga-FAPI-46 PET metrics and staging examinations in PDA;...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov