Depression and Anxiety Trial, Recruiting NCT05541887 Sponsor: University of Florida Condition: Depression and Anxiety
Back to Depression And Anxiety

Depression and Anxiety Trial, Recruiting

NCT05541887
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are generally healthy
  • People with a Body Mass Index (a measure of body weight relative to height) between 18.5 and 29.9, which is considered a normal to healthy range
  • People who weigh at least 110 pounds

Who may not be able to join:

  • People who are pregnant
  • People who are currently breastfeeding
  • People who smoke
  • People who have diabetes
  • People who drink heavily
  • People whose memory or thinking feels off to them personally, even without a formal diagnosis (as measured by a standard memory and thinking test with a score below 26)
  • People who are unable to understand or complete thinking and memory-based tasks
  • People who take medications that could affect the results of the study, such as stimulant medications
  • People who use cannabis products
  • People who have been formally diagnosed with a mental illness
  • People who have heart or nervous system conditions
  • People with high blood pressure that is not being controlled

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Liwei Gu, PhD, University of Florida

Phone: 479-203-8170

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
30 August 2023
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change from baseline cognitive performance score after intervention/placebo; Change from baseline cognitive performance score after intervention/placebo - continued; Change from baseline cognitive performance score after intervention/placebo - continued; Change from baseline monoamine oxidase (MAOs) activity; Change from baseline neurotransmitters; Change from baseline brain-derived neurotrophic factors; Change from baseline cortisol, TNF-α, high sensitivity C-reactive protein, and LPS binding protein

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov