Phase 1 Colorectal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be 18 years old or older.
• The tumor being studied must be at least 1 cm (about half an inch) across, as seen on a scan.
• You must be able to lie still in a PET/CT scanner for at least 70 minutes.
• You must have had a recent scan (such as an MRI or CT) that shows the tumor, so it can be compared to the new PET/CT scan.
• You must have had a physical exam within the last 28 days and certain blood tests within the last 14 days before the PET scan.
• You must be willing to sign a consent form confirming you understand this is a research study.
• Women who could become pregnant must not currently be pregnant or breastfeeding.

If you have a brain tumor, you also need to meet these criteria:

• A doctor must have diagnosed, or suspected, a brain tumor based on clinical assessment and MRI scan — this includes tumors that are new, remaining after treatment, or have come back.

If you have a neuroendocrine tumor outside the brain, you also need to meet these criteria:

• Your neuroendocrine tumor must have been confirmed by a tissue biopsy and be a well-differentiated (slower-growing) type that has spread to other parts of the body.
• You must be well enough to carry out basic daily activities (confirm with trial site).
• You may be on certain long-term hormone-like medications (called somatostatin analogs) for more than 3 months, but this is not required.

If you have breast cancer, you also need to meet these criteria:

• A doctor must have diagnosed breast cancer based on clinical and imaging findings.
• You must be well enough to carry out basic daily activities (confirm with trial site).

If you have rectal cancer, you also need to meet these criteria:

• Your colorectal cancer must have been confirmed by a tissue biopsy and must be located in the rectum.
• You must be well enough to carry out basic daily activities (confirm with trial site).

Who may not be able to join:

• You are currently pregnant or breastfeeding.

For brain tumor patients:

• You have severely raised pressure in your skull, uncontrolled seizures, or another urgent condition needing immediate medical treatment.
• You have had brain tumor surgery or radiation treatment within 1 month before the planned PET scan.

For neuroendocrine tumor patients:

• You have received any treatment directed at the tumor within the past 3 months in the area to be scanned.
• You are currently receiving certain targeted drug therapies (such as sunitinib or everolimus) or chemotherapy (such as capecitabine or temozolomide).
• You have taken a medication called telotristat ethyl within the past month.

For breast cancer patients:

• You have had surgery on the tumor, or radiation or chemotherapy, within the past month.

For rectal cancer patients:

• You have active inflammatory bowel disease (such as Crohn's disease or ulcerative colitis) that affects the rectum.

Important: Always verify eligibility with the trial site directly before applying.