Early Phase 1 Lung Cancer Trial, Not Yet Recruiting NCT05557708 Sponsor: Yusuf Menda Condition: Lung Cancer
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Early Phase 1 Lung Cancer Trial, Not Yet Recruiting

NCT05557708
Not Yet Recruiting Early Phase 1

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are able to give their own independent consent to participate.
  • People whose bone marrow is working well enough, shown by blood counts meeting minimum levels for platelets, red blood cells (haemoglobin), and white blood cells (neutrophils).
  • People whose kidneys are functioning well enough, based on a calculation of how well the kidneys filter the blood (confirm with trial site for exact measurement method).
  • People whose liver is functioning well enough, based on blood test results for liver-related markers falling within acceptable ranges.
  • People whose cancer has not responded to initial treatment, or who have chosen not to continue with other treatments known to be beneficial.
  • People who have at least one tumour or affected area measuring 2 cm or larger that shows a specific protein marker (called CXCR4) on a specialised imaging scan (Lead-203 Pentixather SPECT/CT).

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have had major surgery within 4 weeks before giving consent.
  • People who have taken part in another experimental treatment study within 4 weeks before giving consent.
  • People with serious uncontrolled health conditions, including active infections requiring delayed treatment or hospitalisation, certain heart conditions, severe liver disease, or mental health or personal circumstances that would make it difficult to follow the study requirements.
  • People who have previously had a solid organ transplant (such as a kidney, liver, or heart transplant).
  • People who have received chemotherapy or cancer-fighting drug treatments within 21 days before giving consent (or within 42 days for a specific type of chemotherapy called nitrosoureas).
  • People who have received antibody-based treatments within 21 days before giving consent.
  • People who have had a bone marrow or stem cell transplant from a donor, or any stem cell infusion, within 84 days before giving consent.
  • People who are currently pregnant.
  • People who are currently breastfeeding.
  • People who are not willing to follow the birth control requirements during the study.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Yusuf Menda, MD, University of Iowa

Phone: 319-356-3214

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Early Phase 1
Sponsor
Yusuf Menda
Registry
ClinicalTrials.gov
Start date
1 July 2026
Est. completion
30 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Determine the recommended phase 2 dose of 212-Lead Pentixather

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov