Gastro-oesophageal Reflux Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have had ongoing acid reflux symptoms — such as heartburn or regurgitation — at least twice a week for the past 6 months
• People who have had a special acidity test (called an ambulatory pH study) that has confirmed acid reflux is occurring

Who may not be able to join:

• People who are unwilling or unable to participate or give their consent to join the trial
• People younger than 18 years old or older than 80 years old
• People who are allergic to or cannot tolerate medications called PPIs (proton pump inhibitors, a common type of acid reflux medication)
• People who have a large hiatal hernia (where part of the stomach pushes up into the chest) measuring more than 3 cm, with a specific severity grading (confirm with trial site)
• People who have Barrett's oesophagus (a condition where the lining of the food pipe is changed by long-term acid damage)
• People who have a narrowing of the food pipe that has previously required treatment
• People who have a serious disorder affecting the movement of food through their digestive system
• People who have a condition called eosinophilic oesophagitis (inflammation of the food pipe caused by a type of white blood cell)
• People who have been diagnosed with delayed stomach emptying (gastroparesis), confirmed by a gastric emptying test
• People who have previously had surgery on the stomach or food pipe, including fundoplication, myotomy, or LINX device placement
• People who have severe liver scarring (cirrhosis) along with enlarged veins in the food pipe or stomach (varices)

Important: Always verify eligibility with the trial site directly before applying.