Phase 3 Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 75 years old (inclusive)
• Your doctor expects you to live for at least 3 more months
• You have been diagnosed with pancreatic adenocarcinoma (a specific type of pancreatic cancer), confirmed by a tissue or cell sample
• Your cancer is locally advanced (has grown into nearby blood vessels) but has not spread to distant parts of the body, meeting specific criteria about which blood vessels are affected (confirm with trial site)
• You have at least one area of cancer that can be measured on a scan, following standard guidelines
• You are able to carry out light daily activities with little or no restriction (based on a standard activity scale used by doctors)
• You are medically able to receive a chemotherapy combination of gemcitabine and albumin-bound paclitaxel
• You are able to use a device that delivers electric fields to the tumor, either by yourself or with help from a caregiver
• Any side effects from previous treatments have mostly or fully resolved
• If you are a woman of childbearing age, your pregnancy test is negative, and you agree to use effective birth control during the study and for 6 months after your last chemotherapy dose
• If you are a man, you agree to use effective birth control and not to donate sperm during the study and for 3 months after your last chemotherapy dose
• You are willing to sign a consent form to take part in the trial

Who may not be able to join:

• You have already received first-line (initial) treatment for your pancreatic adenocarcinoma
• You have a known allergy or medical reason why you cannot take gemcitabine or albumin-bound paclitaxel
• You have been treated for another cancer in the past 2 years, with some exceptions such as early-stage prostate cancer, cervical cancer in situ, breast cancer in situ, or certain non-melanoma skin cancers
• Your blood counts, or your heart, liver, or kidney function are outside acceptable ranges as measured by blood tests (confirm with trial site for specific values)
• You need to take high-dose steroid tablets or other immune-suppressing medicines regularly (exceptions may apply for short-term or inhaled/topical steroids — confirm with trial site)
• You have a serious active infection that your doctor feels makes you unsuitable for the trial
• You are known to be HIV-positive
• You have active hepatitis B, active hepatitis C, or another active infection that could affect your treatment
• You have a significant neurological or psychiatric condition (such as epilepsy or dementia) or a history of substance or alcohol misuse in the past year that may affect your ability to follow the study requirements
• You have broken, infected, or unhealed skin in the area where the electric field device would be applied to your body
• You have an implanted electronic medical device, such as a pacemaker
• You have metal medical implants (such as bone screws or plates) in your chest or abdomen
• You have a known allergy to medical adhesives or hydrogels (the materials used with the electric field device)
• You are currently pregnant or breastfeeding
• You have taken part in another drug clinical trial within the past 3 months, or another device clinical trial within the past month
• Your doctor feels you are unlikely to follow the study requirements reliably

Important: Always verify eligibility with the trial site directly before applying.