Phase 3 Gout Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years of age or older (male or female)
- You have been diagnosed with gout, confirmed either by a lab test of fluid from the affected joint, by imaging that shows urate (crystal) deposits in the joint, or by a documented history of gout in that joint or at least 2 gout flares in the past 18 months
- You are currently having a gout flare in the affected joint that started within the last 96 hours (4 days) before your first visit
- You are willing and able to give written consent and follow all trial requirements
Who may not be able to join:
- You have visible or feelable lumps under the skin caused by gout (called tophi)
- You are having a gout flare in 4 or more joints at the same time
- You have rheumatoid arthritis or another active inflammatory joint condition
- There is a sign or suspicion of a joint infection
- You have significant pain from a condition other than gout that could make it hard to accurately rate the pain in the affected joint
- You have been diagnosed with chronic kidney disease or have a known history of kidney problems
- You tested positive for COVID-19 within the 4 weeks before your first visit (if tested)
- You currently have cancer or recently had cancer that required systemic treatment (such as chemotherapy)
- You have a known allergy or sensitivity to OLT1177® or similar medications (confirm with trial site)
- You have a known allergy or sensitivity to paracetamol/acetaminophen (e.g., Tylenol/Panadol)
- You have taken paracetamol/acetaminophen within 4 hours, or other pain medications within 12 hours, before your first visit
- You are taking or plan to take any other medications that are not allowed during the trial, as outlined in the study rules (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +1 833-652-8321
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate the efficacy of dapansutrile as an acute gout flare treatment compared to placebo in reducing joint pain at 72 hours post initial loading dose of IMP
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.